INSULINA LISPRO BULA PDF

aplicação de insulina em diabéticos.1 . *NPL: Protamina Neutra Lispro; ** NPA: Protamina Neutra Aspart; ***NPH: Protamina Neutra Fonte: A atividade da insulina lispro inicia-se aproximadamente 15 minutos após a . médico e leve a embalagem ou bula do medicamento, se possível. Ligue para. subcutaneously administered insulin lispro 8 units from a study in 12 patients with type 1 diabetes is Subcutaneous Insulin Lispro in Type 1 Diabetes Patients*.

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Eli Lilly Nederland B. Date of revision of the text. Posology The dosage should be determined by the physician, according to the requirement of the patient.

Strengths Available for Humalog |

Each KwikPen delivers units in steps of 1 unit. Adjustment of dosage may also be necessary if patients undertake increased physical activity or change their usual diet. To bookmark a medicine you must sign up and log in. MedDRA system organ classes. Humalog may be given shortly before meals. The duration of action of Humalog is dependent on dose, site of injection, blood supply, temperature, and physical activity.

Hipoglicemiante

Each pre-filled pen contains units of insulin lispro in 3 ml solution. In in vitro tests, including binding to insulin receptor sites and effects on growing cells, insulin lispro behaved in a manner that closely resembled human insulin. Marketing authorisation number s 9. Studies also demonstrate that the dissociation of binding to the insulin receptor of insulin lispro is equivalent to human insulin.

Before use 3 years. Pens should not be used if any part looks broken or damaged. When considering the clinical relevance of these kinetics, it is more appropriate to examine the glucose utilisation curves as discussed in 5.

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Before using the KwikPen the user manual included in the package leaflet must be read carefully. Patients with diabetes who are breast-feeding may require adjustments in insulin dose, diet or both.

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Humalog Reusable Discount Card: This information is intended for use by health professionals. Hypoglycaemia and hyperglycaemia Conditions which may make the early warning symptoms of hypoglycaemia different or less bulq include long duration of diabetes, intensified insulin therapy, diabetic nerve disease or medicinal products such as beta-blockers.

When necessary Humalog can be given soon after meals. After injection, the site of injection should not be massaged. Show table of contents Hide table of contents 1. Clear, colourless, aqueous solution.

Humalog 200 Units/ml KwikPen, solution for injection in pre-filled pen

Insulin requirements and dosage adjustment Insulin requirements may be increased during illness or emotional disturbances. View our Humalog coupons and manufacturer promo offers. Name of the medicinal product 2. Cases of oedema have been reported with insulin therapy, particularly if previous poor metabolic control is improved by intensified insulin therapy.

Transferring a patient to another type or brand of insulin Transferring a patient to another type or brand of insulin should be done under strict medical supervision.

Detailed information on this medicinal product is available on the website of the European Medicines Agency http: When administered subcutaneously care should be taken when injecting Humalog to ensure that a blood vessel has not been entered.

Insulin lispro, sold under the brand name Humalog among lispto, is a fast acting insulin analog.

Time to maximum concentration was also similar between formulations. Date of first authorisation: A consequence of the pharmacodynamics of rapid-acting insulin analogues is that if hypoglycaemia occurs, it may occur earlier after an injection when compared with soluble human insulin.

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Ideal for people with no prescription coverage,or drug is not covered However, glucose solution must be given intravenously if glucagon is not available insupina if the patient fails to respond to glucagon. Hypoglycaemia may be associated with listlessness, confusion, palpitations, headache, sweating and vomiting.

Systemic allergy, which is rare but potentially more serious, is a generalised allergy to insulin. Humalog should not be used if it appears cloudy, thickened, or slightly coloured or if solid particles are visible.

bupa The pharmacokinetics of insulin lispro reflect a compound that is rapidly absorbed, and achieves peak blood levels 30 to 70 minutes following subcutaneous injection. The patient should discard the needle after every injection. Insulin lispro has been shown to be equipotent to human insulin on a molar basis but its effect is more rapid and of a shorter duration.

Humalog takes effect rapidly and has a shorter unsulina of activity 2 to 5 hours given subcutaneously as compared with soluble insulin. The advisability of driving should be considered in these circumstances. Patients should be advised to take precautions to avoid hypoglycaemia whilst driving. Bbula rapid onset of activity allows a Humalog injection to be given very close to mealtime. Insulin lispro maintains more rapid absorption and elimination when compared to soluble human insulin in patients with hepatic impairment.

Marketing authorisation holder 8.